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Peptide record

TPDB13218

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13218
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FMKKIVKIGKIARYSHKAKK
Physicochemical Analysis
C111H192N32O23S1
NDCEQLPTW
K
2375.01
11.28
9
0
9
+8
5.34
-0.575
83.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
62.74
2
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
3
I
0
L
7
K
1
M
1
F
0
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 3 L: 0 K: 7 M: 1 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
20
C111H192N32O23S1
2375.01
11.28
+8
5.34
-0.575
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
128 µM
Cytotoxic
0% Cytotoxicity | 128 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020