Peptide record

TPDB13215

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13215
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FLGEWLFVTRKAKRKHKHAA
Physicochemical Analysis
C114H179N35O24
NDCQIMPSY
K
2423.90
11.63
8
1
9
+5
4.00
-0.685
68.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
226.91
1
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
1
E
0
Q
1
G
2
H
0
I
2
L
4
K
0
M
2
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 2 I: 0 L: 2 K: 4 M: 0 F: 2 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
20
C114H179N35O24
2423.90
11.63
+5
4.00
-0.685
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
128 µM
Cytotoxic
0% Cytotoxicity | 128 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Novel Antimicrobial Peptide Discovery Using Machine Learning and Biophysical Selection of Minimal Bacteriocin Domains. | Drug Dev Res | 2020