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Peptide record

TPDB13213

Antibacterial Anticancer Antifungal Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13213
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia dbACP AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KRIGLIRLIGKILRGLRRLG
Physicochemical Analysis
C104H197N37O21
ANDCEQHMFPSTWYV
RL
2301.94
13.01
7
0
9
+7
2.03
0.255
175.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
4
I
5
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 4 L: 5 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C104H197N37O21
2301.94
13.01
+7
2.03
0.255
Evidence Records 5 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
1-31.25 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 1-31.25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 2 Activity

Activity

7% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
7% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 3 Activity

Activity

12% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 4 Activity

Activity

30% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
30% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 5 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes:5% Hemolysis=1-31.25µg/ml 7% Hemolysis=62.5µg/ml 12% Hemolysis=125µg/ml 30% Hemolysis=250µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2016 Oct 11 6:35019.