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Peptide record

TPDB13206

Antibacterial Anticancer Antifungal Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB13206
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RKKRRQRRRCWTKSIPPKPC
Physicochemical Analysis
C110H194N44O24S2
ANDEGHLMFYV
R
2581.15
12.41
10
0
2
+10
8.38
-2.190
19.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5625
217.93
5
Residue Composition
number
0
A
6
R
0
N
0
D
2
C
0
E
1
Q
0
G
0
H
1
I
0
L
4
K
0
M
0
F
3
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 4 M: 0 F: 0 P: 3 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C110H194N44O24S2
2581.15
12.41
+10
8.38
-2.190
Evidence Records 3 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
512 µM
Hemolytic Cytotoxic
3% Hemolysis | 512 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor. | Biomolecules | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor. | Biomolecules | 2019
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biomolecules. 2019 Jul 14 9(7):280.