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Peptide record

TPDB13194

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13194
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AGLAANFLPQILCKIARKC
Physicochemical Analysis
C91H156N26O22S2
DEHMSTWYV
A
2030.52
9.92
3
0
10
+3
-0.34
0.742
123.68
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
6.16
4
Residue Composition
number
4
A
1
R
1
N
0
D
2
C
0
E
1
Q
1
G
0
H
2
I
3
L
2
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 3 K: 2 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C91H156N26O22S2
2030.52
9.92
+3
-0.34
0.742
Evidence Records 1 records
Evidence 1 Activity

Activity

26% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
26% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Relationship and Mode of Action of a Frog Secreted Antibacterial Peptide B1CTcu5 Using Synthetically and Modularly Modified or Deleted (SMMD) Peptides. | PLoS One | 2015