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Peptide record

TPDB13177

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13177
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KRFWPLVPVAINTVAAGIN
Physicochemical Analysis
C98H156N26O23
DCEQHMSY
AV
2066.48
11.49
2
0
11
+2
-0.77
0.684
123.16
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
266.15
3
Residue Composition
number
3
A
1
R
2
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
1
K
0
M
1
F
2
P
0
S
1
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 1 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 1 M: 0 F: 1 P: 2 S: 0 T: 1 W: 1 Y: 0 V: 3
Chemical Descriptors
19
C98H156N26O23
2066.48
11.49
+2
-0.77
0.684
Evidence Records 2 records
Evidence 1 Activity

Activity

38.9% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
38.9% Hemolysis | 256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The Central Hinge Link Truncation of the Antimicrobial Peptide Fowlicidin-3 Enhances Its Cell Selectivity without Antibacterial Activity Loss. | Antimicrob Agents Chemother | 2016
Evidence 2 Activity

Activity

>70% Killing
Toxicity
256 µM
Cytotoxic
>70% Killing | 256 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
The Central Hinge Link Truncation of the Antimicrobial Peptide Fowlicidin-3 Enhances Its Cell Selectivity without Antibacterial Activity Loss. | Antimicrob Agents Chemother | 2016