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Peptide record

TPDB13172

Antibacterial Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13172
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
HTMWRCVRLSACLFSVRRR
Physicochemical Analysis
C102H169N37O23S3
NDEQGIKPY
R
2377.88
12.23
6
0
8
+5
0.57
-0.074
76.84
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
5625
236.56
5
Residue Composition
number
1
A
5
R
0
N
0
D
2
C
0
E
0
Q
0
G
1
H
0
I
2
L
0
K
1
M
1
F
0
P
2
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 2 K: 0 M: 1 F: 1 P: 0 S: 2 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
19
C102H169N37O23S3
2377.88
12.23
+5
0.57
-0.074
Evidence Records 4 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
10% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity and Potential Application in Food Packaging of Peptides Derived from Turbot Viscera Hydrolysate. | J Agric Food Chem | 2020
Evidence 2 Activity

Activity

80% Hemolysis
Toxicity
160 µM
Hemolytic Cytotoxic
80% Hemolysis | 160 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity and Potential Application in Food Packaging of Peptides Derived from Turbot Viscera Hydrolysate. | J Agric Food Chem | 2020
Evidence 3 Activity

Activity

5% Killing
Toxicity
20 µM
Cytotoxic
5% Killing | 20 | µM | target cell: Human hepatocyte cells HL-7702 (L02)

Target

Human hepatocyte cells HL-7702 (L02)

Source & Reference

NA
DBAASP
Antibacterial Activity and Potential Application in Food Packaging of Peptides Derived from Turbot Viscera Hydrolysate. | J Agric Food Chem | 2020
Evidence 4 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis