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Peptide record

TPDB13162

Antibacterial Anticancer Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13162
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
VWPLVIRTVIAGYNLYRAI
Physicochemical Analysis
C107H169N27O24
DCEQHKMFS
IV
2217.69
10.25
2
0
13
+2
-3.27
0.979
158.95
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
8480
382.38
4
Residue Composition
number
2
A
2
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
0
K
0
M
0
F
1
P
0
S
1
T
1
W
2
Y
3
V
Amino Acid Distribution
A: 2 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 0 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 2 V: 3
Chemical Descriptors
19
C107H169N27O24
2217.69
10.25
+2
-3.27
0.979
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
63 µM
Hemolytic Cytotoxic
10% Hemolysis | 63 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The design of a cell-selective fowlicidin-1-derived peptide with both antimicrobial and anti-inflammatory activities. | Eur J Med Chem | 2019