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Peptide record

TPDB13140

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13140
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CancerPPD 2.0 dbACP Antifungipept CAFPdb dbAMP Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
FLSLLPHIASGIASLVSKF
Physicochemical Analysis
C96H154N22O24
RNDCEQMTWY
LS
2000.41
10.10
2
0
11
+1
-2.46
1.332
148.95
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
4
L
1
K
0
M
2
F
1
P
4
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 4 K: 1 M: 0 F: 2 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C96H154N22O24
2000.41
10.10
+1
-2.46
1.332
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus (MIC 5 uM), C. albicans (MIC 15 uM), and very very weak E.coli (200 uM). It also exhibited anticance
Evidence 2 Activity

Activity

MIC
Antibacterial
15 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Active against S. aureus (MIC 5 uM), C. albicans (MIC 15 uM), and very very weak E.coli (200 uM). It also exhibited anticancer activity, including the
Evidence 3 Activity

Activity

MIC
Antifungal
5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus (MIC 5 uM), C. albicans (MIC 15 uM), and very very weak E.coli (200 uM). It also exhibited anticance
Evidence 4 Activity

Activity

MIC
Antifungal
15 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S. aureus (MIC 5 uM), C. albicans (MIC 15 uM), and very very weak E.coli (200 uM). It also exhibited anticancer activity, including the
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
15.82 µM
Hemolytic Cytotoxic
50% Hemolysis | 15.82 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Phylloseptin-PBa1, -PBa2, -PBa3: Three novel antimicrobial peptides from the skin secretion of Burmeister's leaf frog (Phyllomedusa burmeisteri). | Biochem Biophys Res Commun | 2019
Evidence 6 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochem Biophys Res Commun. 2019 Feb 12 509(3):664-673.
Evidence 7 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis