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Peptide record

TPDB13138

Antibacterial Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13138
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
CRKPTFRRLKWKIKFKFKC
Physicochemical Analysis
C119H193N35O21S2
ANDEQGHMSYV
K
2514.18
11.62
9
0
6
+9
2.37
-0.968
41.05
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
223.73
3
Residue Composition
number
0
A
3
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
1
I
1
L
6
K
0
M
3
F
1
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 6 M: 0 F: 3 P: 1 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
19
C119H193N35O21S2
2514.18
11.62
+9
2.37
-0.968
Evidence Records 6 records
Evidence 1 Activity

Activity

0.68±1.05% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
0.68±1.05% Hemolysis | 128 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synergistic antibiotic effect of looped antimicrobial peptide CLP-19 with bactericidal and bacteriostatic agents. | Oncotarget | 2017
Evidence 2 Activity

Activity

38.71±10.05% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
38.71±10.05% Hemolysis | 256 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synergistic antibiotic effect of looped antimicrobial peptide CLP-19 with bactericidal and bacteriostatic agents. | Oncotarget | 2017
Evidence 3 Activity

Activity

72.35±17.50% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
72.35±17.50% Hemolysis | 512 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synergistic antibiotic effect of looped antimicrobial peptide CLP-19 with bactericidal and bacteriostatic agents. | Oncotarget | 2017
Evidence 4 Activity

Activity

3.39±1.44% Killing
Toxicity
128 µg/mL
Cytotoxic
3.39±1.44% Killing | 128 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Synergistic antibiotic effect of looped antimicrobial peptide CLP-19 with bactericidal and bacteriostatic agents. | Oncotarget | 2017
Evidence 5 Activity

Activity

45.53±17.52% Killing
Toxicity
256 µg/mL
Cytotoxic
45.53±17.52% Killing | 256 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Synergistic antibiotic effect of looped antimicrobial peptide CLP-19 with bactericidal and bacteriostatic agents. | Oncotarget | 2017
Evidence 6 Activity

Activity

91.23±30.71% Killing
Toxicity
512 µg/mL
Cytotoxic
91.23±30.71% Killing | 512 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Synergistic antibiotic effect of looped antimicrobial peptide CLP-19 with bactericidal and bacteriostatic agents. | Oncotarget | 2017