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Peptide record

TPDB13136

Antibacterial Anticancer Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13136
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LVIRWVRAGYKLYRAIKKK
Physicochemical Analysis
C113H189N33O22
NDCEQHMFPST
K
2361.95
11.57
7
0
11
+7
0.73
-0.232
123.16
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
8480
359.03
2
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
2
L
4
K
0
M
0
F
0
P
0
S
0
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 2
Chemical Descriptors
19
C113H189N33O22
2361.95
11.57
+7
0.73
-0.232
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
105 µM
Hemolytic Cytotoxic
10% Hemolysis | 105 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The design of a cell-selective fowlicidin-1-derived peptide with both antimicrobial and anti-inflammatory activities. | Eur J Med Chem | 2019