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Peptide record

TPDB13128

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13128
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FLKLLKKVLKKVLPKIFK
Physicochemical Analysis
C111H195N25O19
ARNDCEQGHMSTWY
K
2183.93
11.29
7
0
10
+7
2.15
0.478
162.22
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
5
L
7
K
0
M
2
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 5 K: 7 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C111H195N25O19
2183.93
11.29
+7
2.15
0.478
Evidence Records 4 records
Evidence 1 Activity

Activity

0% Killing
Toxicity
12.5 µg/mL
Cytotoxic
0% Killing | 12.5 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Antibacterial activity of a scorpion-derived peptide and its derivatives in vitro and in vivo | Toxicon | 2020
Evidence 2 Activity

Activity

85% Killing
Toxicity
100 µg/mL
Cytotoxic
85% Killing | 100 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Antibacterial activity of a scorpion-derived peptide and its derivatives in vitro and in vivo | Toxicon | 2020
Evidence 3 Activity

Activity

25% Killing
Toxicity
12.5 µg/mL
Cytotoxic
25% Killing | 12.5 | µg/mL | target cell: Human hepatocyte cells HL-7702 (L02)

Target

Human hepatocyte cells HL-7702 (L02)

Source & Reference

NA
DBAASP
Antibacterial activity of a scorpion-derived peptide and its derivatives in vitro and in vivo | Toxicon | 2020
Evidence 4 Activity

Activity

95% Killing
Toxicity
100 µg/mL
Cytotoxic
95% Killing | 100 | µg/mL | target cell: Human hepatocyte cells HL-7702 (L02)

Target

Human hepatocyte cells HL-7702 (L02)

Source & Reference

NA
DBAASP
Antibacterial activity of a scorpion-derived peptide and its derivatives in vitro and in vivo | Toxicon | 2020