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Peptide record

TPDB13119

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13119
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ITKVIAKLLNRLTKILSK
Physicochemical Analysis
C95H178N26O23
DCEQGHMFPWY
LK
2052.62
11.80
5
0
9
+5
2.33
0.494
173.33
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
4
L
4
K
0
M
0
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 4 K: 4 M: 0 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C95H178N26O23
2052.62
11.80
+5
2.33
0.494
Evidence Records 1 records
Evidence 1 Activity

Activity

72±16% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
72±16% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Helminth Defense Molecules as Design Templates for Membrane Active Antibiotics. | ACS Infect Dis | 2019