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Peptide record

TPDB13099

Antibacterial Anticancer Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13099
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
IVIKSLGKFLKNVGGFAG
Physicochemical Analysis
C88H146N22O21
RDCEQHMPTWY
G
1848.26
10.84
3
0
9
+3
-0.47
0.822
124.44
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
4
G
0
H
2
I
2
L
3
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 2 L: 2 K: 3 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C88H146N22O21
1848.26
10.84
+3
-0.47
0.822
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
<10% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of antimicrobial and cytolytic peptides by computational analysis of bacterial, algal, and invertebrate proteomes. | Amino Acids | 2020
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: <10% Hemolysis=50 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2020 Oct 52(10):1403-1412