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Peptide record

TPDB13095

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13095
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
AFWKKFFKKFFKSAKKFG
Physicochemical Analysis
C118H168N26O20
RNDCEQHILMPTYV
K
2270.79
11.29
7
0
9
+7
-1.90
-0.500
11.11
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
242.21
1
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
7
K
0
M
6
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 7 M: 0 F: 6 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C118H168N26O20
2270.79
11.29
+7
-1.90
-0.500
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Killing
Toxicity
15 µM
Cytotoxic
50% Killing | 15 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Effects of Hydrophobic Amino Acid Substitutions on Antimicrobial Peptide Behavior | Probiotics Antimicrob Proteins | 2018