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Peptide record

TPDB13089

Antibacterial Anticancer Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13089
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
ILKPKLWKLTVVARKIIK
Physicochemical Analysis
C105H187N27O20
NDCEQGHMFSY
K
2147.81
11.85
6
0
10
+6
1.86
0.439
167.78
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
256.07
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
3
L
5
K
0
M
0
F
1
P
0
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 3 K: 5 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
18
C105H187N27O20
2147.81
11.85
+6
1.86
0.439
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
<10% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of antimicrobial and cytolytic peptides by computational analysis of bacterial, algal, and invertebrate proteomes. | Amino Acids | 2020
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: <10% Hemolysis=50 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2020 Oct 52(10):1403-1412