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Peptide record

TPDB13080

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13080
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FQRYFHRYARFLAKIWKG
Physicochemical Analysis
C117H167N33O22
NDCEMPSTV
RF
2387.82
11.45
6
0
10
+5
-2.37
-0.644
54.44
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
8480
355.14
3
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
1
Q
1
G
1
H
1
I
1
L
2
K
0
M
3
F
0
P
0
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 1 K: 2 M: 0 F: 3 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
18
C117H167N33O22
2387.82
11.45
+5
-2.37
-0.644
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
1.3-10.4 µM
Hemolytic Cytotoxic
<10% Hemolysis | 1.3-10.4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Adepamycin: design, synthesis and biological properties of a new peptide with antimicrobial properties | Arch Biochem Biophys | 2020
Evidence 2 Activity

Activity

60% Hemolysis
Toxicity
335 µM
Hemolytic Cytotoxic
60% Hemolysis | 335 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Adepamycin: design, synthesis and biological properties of a new peptide with antimicrobial properties | Arch Biochem Biophys | 2020