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Peptide record

TPDB13077

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13077
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
KKVWFIFHVCPKLKQRIL
Physicochemical Analysis
C112H179N29O20S1
ANDEGMSTY
K
2283.90
10.98
6
0
9
+5
0.81
0.211
118.89
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
240.82
2
Residue Composition
number
0
A
1
R
0
N
0
D
1
C
0
E
1
Q
0
G
1
H
2
I
2
L
4
K
0
M
2
F
1
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 1 I: 2 L: 2 K: 4 M: 0 F: 2 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
18
C112H179N29O20S1
2283.90
10.98
+5
0.81
0.211
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note tha
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP

Other

ctive against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 4 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Escherichia coli ATCC 11775

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note tha
Evidence 5 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from
Evidence 6 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ctive against E. coli ATCC 11775 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 16 ug/ml), and C. albicans ATCC 14053 (MIC 16 ug/ml). Note that the mature sequence may differ from the synthetic peptide used here.
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 100 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016
Evidence 8 Activity

Activity

8% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
8% Hemolysis | 200 | µg/mL | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
De Novo Transcriptome Analysis and Detection of Antimicrobial Peptides of the American Cockroach Periplaneta americana (Linnaeus). | PLoS One | 2016