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Peptide record

TPDB13066

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB13066
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KNIRRIIRKIIHIIKKYG
Physicochemical Analysis
C105H188N34O21
ADCEQLMFPSTWV
I
2262.86
12.16
8
0
8
+7
4.67
-0.333
151.67
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
65.85
2
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
0
E
0
Q
1
G
1
H
7
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 7 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
18
C105H188N34O21
2262.86
12.16
+7
4.67
-0.333
Evidence Records 1 records
Evidence 1 Activity

Activity

76% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
76% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | J Antimicrob Chemother | 2011