Peptide record

TPDB13065

Antibacterial Anticancer Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13065
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
RKCVRVQLIKNGKKITAF
Physicochemical Analysis
C94H168N30O22S1
DEHMPSWY
K
2102.62
11.63
6
0
7
+6
4.15
-0.244
102.78
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
4
Residue Composition
number
1
A
2
R
1
N
0
D
1
C
0
E
1
Q
1
G
0
H
2
I
1
L
4
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 2 L: 1 K: 4 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C94H168N30O22S1
2102.62
11.63
+6
4.15
-0.244
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8.4 µM

Target

A. hydrophila

Source & Reference

NA

Other

Active against E. coli, A. hydrophila (MIC 8.4 uM), S. aureus and M. luteus (MIC 7.2 uM). Recombinant full length protein is also active.
Evidence 2 Activity

Activity

MIC
Antibacterial
7.2 µM

Target

M. luteus

Source & Reference

NA

Other

Active against E. coli, A. hydrophila (MIC 8.4 uM), S. aureus and M. luteus (MIC 7.2 uM). Recombinant full length protein is also active.
Evidence 3 Activity

Activity

MIC
Antifungal
8.4 µM

Target

A. hydrophila

Source & Reference

Antifungipept

Other

Active against E. coli, A. hydrophila (MIC 8.4 uM), S. aureus and M. luteus (MIC 7.2 uM). Recombinant full length protein is also active.
Evidence 4 Activity

Activity

MIC
Antifungal
7.2 µM

Target

M. luteus

Source & Reference

Antifungipept

Other

Active against E. coli, A. hydrophila (MIC 8.4 uM), S. aureus and M. luteus (MIC 7.2 uM). Recombinant full length protein is also active.
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and Functional Characterization of Ribosomal Protein S23 as a New Member of Antimicrobial Protein | Dev Comp Immunol | 2020