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Peptide record

TPDB13046

Antibacterial Anticancer Antifungal Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB13046
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
GALKGCWTKSIPPKPCK
Physicochemical Analysis
C82H136N22O20S2
RNDEQHMFYV
K
1814.24
10.17
4
0
4
+4
2.23
-0.500
51.76
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5625
310.05
4
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
2
G
0
H
1
I
1
L
4
K
0
M
0
F
3
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 1 K: 4 M: 0 F: 0 P: 3 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C82H136N22O20S2
1814.24
10.17
+4
2.23
-0.500
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human colon endothelial cells FHC

Target

Human colon endothelial cells FHC

Source & Reference

NA
DBAASP
Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide-PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer. | Sci Rep | 2018
Evidence 2 Activity

Activity

IC50
Toxicity
50.2 µM
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: HKE3: IC50=50.2 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2018 Sep 28 8(1):14502.