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Peptide record

TPDB13045

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB13045
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IGRHFKRRNSIWGICWF
Physicochemical Analysis
C102H150N32O20S1
ADEQLMPTYV
RI
2176.58
12.12
5
0
7
+4
-2.18
-0.347
68.82
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
11000
505.38
3
Residue Composition
number
0
A
3
R
1
N
0
D
1
C
0
E
0
Q
2
G
1
H
3
I
0
L
1
K
0
M
2
F
0
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 2 H: 1 I: 3 L: 0 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
17
C102H150N32O20S1
2176.58
12.12
+4
-2.18
-0.347
Evidence Records 1 records
Evidence 1 Activity

Activity

75% Killing
Toxicity
59.2 µM
Cytotoxic
75% Killing | 59.2 | µM | target cell: Mouse fibroblasts McCoy

Target

Mouse fibroblasts McCoy

Source & Reference

NA
DBAASP
The Hirudo Medicinalis Microbiome Is a Source of New Antimicrobial Peptides. | Int J Mol Sci | 2020