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Peptide record

TPDB13043

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB13043
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ATKKCGLFKILKGVGKI
Physicochemical Analysis
C84H150N22O19S1
RNDEQHMPSWY
K
1804.31
10.71
5
0
7
+5
1.91
0.382
114.71
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
1
C
0
E
0
Q
3
G
0
H
2
I
2
L
5
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C84H150N22O19S1
1804.31
10.71
+5
1.91
0.382
Evidence Records 1 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of a new synthetic peptide loaded in polylactic acid or poly(lactic-co-glycolic) acid nanoparticles against Pseudomonas aeruginosa, Escherichia coli O157:H7 and methicillin resistant Staphylococcus aureus (MRSA). | Nanotechnology | 2017