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Peptide record

TPDB13040

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB13040
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
SFIKRSLKLIKSLVLIK
Physicochemical Analysis
C95H172N24O21
ANDCEQGHMPTWY
LK
1986.56
11.80
5
0
9
+5
0.93
0.776
177.65
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
4
L
4
K
0
M
1
F
0
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 4 K: 4 M: 0 F: 1 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C95H172N24O21
1986.56
11.80
+5
0.93
0.776
Evidence Records 2 records
Evidence 1 Activity

Activity

26% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
26% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A New Synthetic Peptide with In vitro Antibacterial Potential Against Escherichia coli O157:H7 and Methicillin-Resistant Staphylococcus aureus (MRSA). | Probiotics Antimicrob Proteins | 2016
Evidence 2 Activity

Activity

50% Cell death
Toxicity
40.6 µM
Cytotoxic
50% Cell death | 40.6 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
A New Synthetic Peptide with In vitro Antibacterial Potential Against Escherichia coli O157:H7 and Methicillin-Resistant Staphylococcus aureus (MRSA). | Probiotics Antimicrob Proteins | 2016