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Peptide record

TPDB13022

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB13022
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifungipept i2APP AI4AVP APD_complete APD_hemolytic Hemolytic2
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IKITTMLAKLGKVLAHV
Physicochemical Analysis
C85H154N22O20S1
RNDCEQFPSWY
LK
1836.35
10.84
4
0
10
+3
1.49
1.035
160.59
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
3
L
3
K
1
M
0
F
0
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 3 K: 3 M: 1 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
17
C85H154N22O20S1
1836.35
10.84
+3
1.49
1.035
Evidence Records 3 records
Evidence 1 Activity

Activity

Hemolysis
[Ref.2578459] Hemolysis: ED50=4.0±0.05 µg/ml. Histamine release: ED50=16.3±0.5 µg/ml against guinea pig erythrocytes.

Target

guinea pig erythrocytes

Source & Reference

APD_complete APD_hemolytic
DRAMP4
J Biol Chem. 1985 Feb 10 260(3):1437-144.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.2578459] Hemolysis: ED50=4.0±0.05 µg/ml. Histamine release: ED50=16.3±0.5 µg/ml against guinea pig erythrocytes.

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 1985 Feb 10 260(3):1437-144.
Evidence 3 Hemolysis

Activity

[Ref.2578459] Hemolysis: ED50=4.0±0.05 µg/ml. Histamine release: ED50=16.3±0.5 µg/ml against guinea pig erythrocytes.
Hemolysis

Target

guinea pig erythrocytes

Source & Reference

APD_complete APD_hemolytic
J Biol Chem. 1985 Feb 10 260(3):1437-144.
DRAMP4
APD_complete APD_hemolytic