Peptide record

TPDB13005

alpha chain (208-223) Beta-conglycinin Antibacterial Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB13005
alpha chain (208-223) Beta-conglycinin
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP DBAASP
standard
No
A 16-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KNQYGRIRVLQRFNQR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C90H150N34O23
ADCEHMPSTW
R
2076.39
12.41
5
0
5
+5
4.84
-1.613
66.88
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
0.72
6
Residue Composition
number
0
A
4
R
2
N
0
D
0
C
0
E
3
Q
1
G
0
H
1
I
1
L
1
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 4 N: 2 D: 0 C: 0 E: 0 Q: 3 G: 1 H: 0 I: 1 L: 1 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
16 reviewed residue count
C90H150N34O23 sequence-only estimate (linear, free termini)
2076.39 sequence-only estimate (linear, free termini)
12.41 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
4.84 sequence-only estimate (linear, free termini)
-1.613 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

40% Hemolysis
Toxicity
50-500 µM
Hemolytic Cytotoxic
40% Hemolysis | 50-500 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of multifunctional cationic and amphipathic peptides from soybean proteins. | Biopolymers | 2017
Evidence 2 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP