Back to search

Peptide record

TPDB12988

Antibacterial Antifungal Hemolysis Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12988
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLWDVIKKVASVIGGL
Physicochemical Analysis
C78H131N19O20
RNCEQHMFPTY
GV
1655.01
9.88
2
1
9
+1
-0.18
1.050
158.12
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
332.32
1
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
3
G
0
H
2
I
2
L
2
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 2 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
16
C78H131N19O20
1655.01
9.88
+1
-0.18
1.050
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
16.85 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 16.85 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity. | Peptides | 2019
Evidence 2 Activity

Activity

IC50
Toxicity
>32 µg/mL
Cytotoxic
IC50 | >32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Understanding interactions of Citropin 1.1 analogues with model membranes and their influence on biological activity. | Peptides | 2019
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis