Back to search

Peptide record

TPDB12980

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12980
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
SVAGRAMRIGLRFVLM
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C78H137N25O18S2
NDCEQHKPTWY
R
1777.22
12.70
3
0
10
+3
0.76
0.975
121.88
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
3
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
2
L
0
K
2
M
1
F
0
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 0 M: 2 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
16 reviewed residue count
C78H137N25O18S2 sequence-only estimate (linear, free termini)
1777.22 sequence-only estimate (linear, free termini)
12.70 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
0.76 sequence-only estimate (linear, free termini)
0.975 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide selection from Lippia spp leaf transcriptomes | Peptides | 2020