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Peptide record

TPDB12978

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB12978
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RRRRKLDLKLDLKLDL
Physicochemical Analysis
C90H167N31O23
ANCEQGHIMFPSTWYV
L
2051.51
11.39
7
3
6
+4
6.54
-1.087
146.25
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
4
R
0
N
3
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 3 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C90H167N31O23
2051.51
11.39
+4
6.54
-1.087
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties. | Biomaterials | 2015
Evidence 2 Activity

Activity

10% Killing
Toxicity
100 µg/mL
Cytotoxic
10% Killing | 100 | µg/mL | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties. | Biomaterials | 2015