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Peptide record

TPDB12973

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB12973
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
IAKIAGKIAKIAGKIA
Physicochemical Analysis
C73H136N20O17
RNDCEQHLMFPSTWYV
AI
1566.01
11.00
4
0
10
+4
1.58
0.944
153.12
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
5
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 5 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C73H136N20O17
1566.01
11.00
+4
1.58
0.944
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Terminal Charges Modulate the Pore Forming Activity of Cationic Amphipathic Helices. | Biochim Biophys Acta | 2020