Back to search

Peptide record

TPDB12962

Antibacterial Anticancer Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12962
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
AFALIAGALYRIFHRR
Physicochemical Analysis
C89H139N27O18
NDCEQKMPSTWV
A
1875.25
12.11
4
0
11
+3
-2.22
0.688
122.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
79.46
1
Residue Composition
number
4
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
2
L
0
K
0
M
2
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
16
C89H139N27O18
1875.25
12.11
+3
-2.22
0.688
Evidence Records 4 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
16 µM
Hemolytic Cytotoxic
<5% Hemolysis | 16 | µM | target cell: Goat erythrocytes

Target

Goat erythrocytes

Source & Reference

NA
DBAASP
LHH1, a novel antimicrobial peptide with anti-cancer cell activity identified from Lactobacillus casei HZ1. | AMB Express | 2020
Evidence 2 Activity

Activity

32% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
32% Hemolysis | 128 | µM | target cell: Goat erythrocytes

Target

Goat erythrocytes

Source & Reference

NA
DBAASP
LHH1, a novel antimicrobial peptide with anti-cancer cell activity identified from Lactobacillus casei HZ1. | AMB Express | 2020
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
187.2 µM
Hemolytic Cytotoxic
50% Hemolysis | 187.2 | µM | target cell: Goat erythrocytes

Target

Goat erythrocytes

Source & Reference

NA
DBAASP
LHH1, a novel antimicrobial peptide with anti-cancer cell activity identified from Lactobacillus casei HZ1. | AMB Express | 2020
Evidence 4 Activity

Activity

HC50
Toxicity
187.2 µM
Hemolytic Cytotoxic
Hemolytic_activity: Goat erythrocytes: HC50=187.2 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
AMB Express. 2020 Nov 11 10(1):204.