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Peptide record

TPDB12961

Antibacterial Anticancer Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB12961
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SWKKFFKKARSLPKLF
Physicochemical Analysis
C100H155N25O19
NDCEQGHIMTYV
K
2011.49
11.85
6
0
7
+6
-0.06
-0.644
55.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
273.43
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
5
K
0
M
3
F
1
P
2
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 5 M: 0 F: 3 P: 1 S: 2 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C100H155N25O19
2011.49
11.85
+6
-0.06
-0.644
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>128 µg/mL
Cytotoxic
50% Cell death | >128 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Computational antimicrobial peptide design and evaluation against multidrug-resistant clinical isolates of bacteria. | J Biol Chem | 2018
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2018 Mar 9 293(10):3492-3509.