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Peptide record

TPDB12941

Antibacterial Antiparasitic Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB12941
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbAMP 3.0 ToxinPred 3.0
standard
No
A 15-aa standard-residue multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
FTKIYGSRLQKVLGN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C79H130N22O21
ADCEHMPW
GLK
1724.04
10.72
3
0
6
+3
1.38
-0.253
97.33
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
0.86
5
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
1
Q
2
G
0
H
1
I
2
L
2
K
0
M
1
F
0
P
1
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 2 K: 2 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
15 reviewed residue count
C79H130N22O21 sequence-only estimate (linear, free termini)
1724.04 sequence-only estimate (linear, free termini)
10.72 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.38 sequence-only estimate (linear, free termini)
-0.253 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 500 | µg/mL | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Two short antimicrobial peptides derived from prosaposin-like proteins in the starry flounder (Platichthys stellatus) | Fish Shellfish Immunol | 2020