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Peptide record

TPDB12940

Antibacterial Antifungal standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB12940
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
VAIALKAAHYHTAKE
Physicochemical Analysis
C74H119N21O20
RNDCQGMFPSW
A
1622.89
9.65
4
1
9
+1
3.47
0.120
104.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
91.81
2
Residue Composition
number
5
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
2
H
1
I
1
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 2 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
15
C74H119N21O20
1622.89
9.65
+1
3.47
0.120
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Enterococcus faecalis 29212

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
At pH 7.4, it was not active. At pH 5.4, active against E. faecalis 29212 (MIC 4 ug/ml) and S. aureus 29213 (MIC 0.25 ug/ml). The activity was enhanced in the presence of Zn2+ (
Evidence 2 Activity

Activity

MIC
Antibacterial
0.25 µg/mL

Target

Staphylococcus aureus 29213

Source & Reference

dbAMP

Other

pH 7.4, it was not active. At pH 5.4, active against E. faecalis 29212 (MIC 4 ug/ml) and S. aureus 29213 (MIC 0.25 ug/ml). The activity was enhanced in the presence of Zn2+ (MIC 0.5 ug/ml). Inactive: E. coli 259
Evidence 3 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

K.pneumoniae 13883

Source & Reference

dbAMP

Other

anced in the presence of Zn2+ (MIC 0.5 ug/ml). Inactive: E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

P.aeruginosa 15442

Source & Reference

dbAMP

Other

/ml). Inactive: E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Enterococcus faecalis 29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
At pH 7.4, it was not active. At pH 5.4, active against E. faecalis 29212 (MIC 4 ug/ml) and S. aureus 29213 (MIC 0.25 ug/ml). The activity was enhanced in the presence of Zn2+ (
Evidence 6 Activity

Activity

MIC
Antifungal
0.25 µg/mL

Target

Staphylococcus aureus 29213

Source & Reference

dbAMP CAFPdb Antifungipept

Other

pH 7.4, it was not active. At pH 5.4, active against E. faecalis 29212 (MIC 4 ug/ml) and S. aureus 29213 (MIC 0.25 ug/ml). The activity was enhanced in the presence of Zn2+ (MIC 0.5 ug/ml). Inactive: E. coli 259
Evidence 7 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

K.pneumoniae 13883

Source & Reference

dbAMP CAFPdb Antifungipept

Other

anced in the presence of Zn2+ (MIC 0.5 ug/ml). Inactive: E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml).
Evidence 8 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

P.aeruginosa 15442

Source & Reference

dbAMP CAFPdb Antifungipept

Other

/ml). Inactive: E. coli 25922 (MIC > 128 ug/ml), K.pneumoniae 13883 (MIC >128 ug/ml), and P.aeruginosa 15442 (MIC>128 ug/ml).