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Peptide record

TPDB12938

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB12938
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RKEKIKKRIGKIDRL
Physicochemical Analysis
C83H157N29O20
ANCQHMFPSTWYV
K
1881.34
11.58
8
2
4
+6
9.15
-1.540
104.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
3
R
0
N
1
D
0
C
1
E
0
Q
1
G
0
H
3
I
1
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
15
C83H157N29O20
1881.34
11.58
+6
9.15
-1.540
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>250 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel, rationally designed, hybrid antimicrobial peptide, inspired by cathelicidin and aurein, exhibits membrane-active mechanisms against Pseudomonas aeruginosa. | Sci Rep | 2020