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Peptide record

TPDB12933

Antibacterial Anticancer Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB12933
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, PD_Hemolysis, and other sources, with an available 3D structural model.
Sequence
ITKWLLNAIKKGFKL
Physicochemical Analysis
C87H145N21O18
RDCEQHMPSYV
K
1773.24
11.00
4
0
8
+4
-0.92
0.260
136.67
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
310.17
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
3
L
4
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C87H145N21O18
1773.24
11.00
+4
-0.92
0.260
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
21.9 µM
Hemolytic Cytotoxic
10% Hemolysis | 21.9 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of antimicrobial and cytolytic peptides by computational analysis of bacterial, algal, and invertebrate proteomes. | Amino Acids | 2020
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 10% Hemolysis=21.9 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2020 Oct 52(10):1403-1412
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis