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Peptide record

TPDB12931

Antibacterial Antifungal Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB12931
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FFQELKEGWKNIKKA
Physicochemical Analysis
C89H136N22O22
RDCHMPSTYV
K
1866.19
10.16
4
2
6
+2
3.86
-1.013
58.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
294.72
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
2
E
1
Q
1
G
0
H
1
I
1
L
4
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 2 Q: 1 G: 1 H: 0 I: 1 L: 1 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C89H136N22O22
1866.19
10.16
+2
3.86
-1.013
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
7.8 µM

Target

A. salmonicida RFAS1

Source & Reference

NA

Other

Active against A. salmonicida RFAS1 (MIC 7.8 uM), V. alginolyticus KCCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228
Evidence 2 Activity

Activity

MIC
Antibacterial
7.8 µM

Target

V. alginolyticus KCCM2928

Source & Reference

NA

Other

Active against A. salmonicida RFAS1 (MIC 7.8 uM), V. alginolyticus KCCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228 (MIC 15.6 uM), and E. tarda FP4130 (MIC
Evidence 3 Activity

Activity

MIC
Antibacterial
15.6 µM

Target

S. iniae FP5228

Source & Reference

NA

Other

S1 (MIC 7.8 uM), V. alginolyticus KCCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228 (MIC 15.6 uM), and E. tarda FP4130 (MIC 62.5 uM). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antibacterial
62.5 µM

Target

E. tarda FP4130

Source & Reference

NA

Other

CCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228 (MIC 15.6 uM), and E. tarda FP4130 (MIC 62.5 uM). Updated 7/2021
Evidence 5 Activity

Activity

MIC
Antifungal
7.8 µM

Target

A. salmonicida RFAS1

Source & Reference

Antifungipept

Other

Active against A. salmonicida RFAS1 (MIC 7.8 uM), V. alginolyticus KCCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228
Evidence 6 Activity

Activity

MIC
Antifungal
7.8 µM

Target

V. alginolyticus KCCM2928

Source & Reference

Antifungipept

Other

Active against A. salmonicida RFAS1 (MIC 7.8 uM), V. alginolyticus KCCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228 (MIC 15.6 uM), and E. tarda FP4130 (MIC
Evidence 7 Activity

Activity

MIC
Antifungal
15.6 µM

Target

S. iniae FP5228

Source & Reference

Antifungipept

Other

S1 (MIC 7.8 uM), V. alginolyticus KCCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228 (MIC 15.6 uM), and E. tarda FP4130 (MIC 62.5 uM). Updated 7/2021
Evidence 8 Activity

Activity

MIC
Antifungal
62.5 µM

Target

E. tarda FP4130

Source & Reference

Antifungipept

Other

CCM2928 (MIC 7.8 uM), V. ordalii KCCM41669 (NIC 2 uM), S. iniae FP5228 (MIC 15.6 uM), and E. tarda FP4130 (MIC 62.5 uM). Updated 7/2021
Evidence 9 Activity

Activity

0% Hemolysis
Toxicity
500 µM
Hemolytic Cytotoxic
0% Hemolysis | 500 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Gene expressions and biological activities of two novel antimicrobial peptides (AMPs) isolated from leucocytes of the rock bream, Oplegnathus fasciatus | Aquaculture | 2018
Evidence 10 Activity

Activity

100% Hemolysis
Toxicity
1000 µM
Hemolytic Cytotoxic
100% Hemolysis | 1000 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Gene expressions and biological activities of two novel antimicrobial peptides (AMPs) isolated from leucocytes of the rock bream, Oplegnathus fasciatus | Aquaculture | 2018