Back to search

Peptide record

TPDB12929

Antibacterial Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12929
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard-residue multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GGHRRWKIVVIRWRR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C90H147N35O16
ANDCEQLMFPSTY
R
1975.38
13.00
7
0
6
+6
4.02
-0.987
90.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
5.57
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
2
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
15 reviewed residue count
C90H147N35O16 sequence-only estimate (linear, free termini)
1975.38 sequence-only estimate (linear, free termini)
13.00 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
4.02 sequence-only estimate (linear, free termini)
-0.987 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human dermal fibroblasts

Target

Human dermal fibroblasts

Source & Reference

NA
DBAASP
Cu-ATCUN Derivatives of Sub5 Exhibit Enhanced Antimicrobial Activity via Multiple Modes of Action. | ACS Chem Biol | 2019