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Peptide record

TPDB12924

Antibacterial Anticancer Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB12924
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
WRRWRRRWRRRWRRW
Physicochemical Analysis
C115H172N50O16
ANDCEQGHILKMFPSTYV
R
2510.96
13.35
10
0
5
+10
-1.15
-3.300
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
27500
1095.20
0
Residue Composition
number
0
A
10
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
15
C115H172N50O16
2510.96
13.35
+10
-1.15
-3.300
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>256 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Design of Heptad Amphiphiles To Enhance Cell Selectivity, Salt Resistance, Antibiofilm Properties and Their Membrane-Disruptive Mechanism. | J Med Chem | 2017