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Peptide record

TPDB12918

Antibacterial Anticancer Hemolysis Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB12918
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, PD_Hemolysis, and other sources, with an available 3D structural model.
Sequence
LFSIIWKLNRKLIKA
Physicochemical Analysis
C90H151N23O18
DCEQGHMPTYV
ILK
1843.33
11.73
4
0
9
+4
-1.43
0.540
162.67
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
298.37
2
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
3
L
3
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 3 K: 3 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
15
C90H151N23O18
1843.33
11.73
+4
-1.43
0.540
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
37.3 µM
Hemolytic Cytotoxic
10% Hemolysis | 37.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of antimicrobial and cytolytic peptides by computational analysis of bacterial, algal, and invertebrate proteomes. | Amino Acids | 2020
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 10% Hemolysis=37.3 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2020 Oct 52(10):1403-1412
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis