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Peptide record

TPDB12900

Antibacterial Antifungal Antiparasitic Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12900
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP dbAMP 3.0 ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LKLLGIVKKVLGAI
Physicochemical Analysis
C71H133N17O15
RNDCEQHMFPSTWY
L
1464.94
10.84
3
0
9
+3
0.10
1.564
215.71
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
4
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
14
C71H133N17O15
1464.94
10.84
+3
0.10
1.564
Evidence Records 7 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
New Mastoparan Peptides in the Venom of the Solitary Eumenine Wasp Eumenes micado. | Toxins (Basel) | 2019
Evidence 2 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
New Mastoparan Peptides in the Venom of the Solitary Eumenine Wasp Eumenes micado. | Toxins (Basel) | 2019
Evidence 3 Activity

Activity

IC50
Toxicity
42.35±1.37 µM
Cytotoxic
IC50 | 42.35±1.37 | µM | target cell: Human pancreas epithelial cells HPNE

Target

Human pancreas epithelial cells HPNE

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 4 Activity

Activity

IC50
Toxicity
18.21±0.21 µM
Cytotoxic
IC50 | 18.21±0.21 | µM | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 5 Activity

Activity

IC50
Toxicity
>50 µM
Cytotoxic
IC50 | >50 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 6 Activity

Activity

IC50
Toxicity
>50 µM
Cytotoxic
IC50 | >50 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 7 Activity

Activity

<10% Hemolysis
Toxicity
250 µM
Cytotoxic
<10% Hemolysis | 250 | µM | target cell: Mouse splenocytes

Target

Mouse splenocytes

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025