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Peptide record

TPDB12880

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12880
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
WKWKWENGKWKWKW
Physicochemical Analysis
C107H138N26O18
ARDCQHILMFPSTYV
W
2076.44
10.71
5
1
6
+4
-3.70
-2.307
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
33000
1589.26
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
0
L
5
K
0
M
0
F
0
P
0
S
0
T
6
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 6 Y: 0 V: 0
Chemical Descriptors
14
C107H138N26O18
2076.44
10.71
+4
-3.70
-2.307
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
<5% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Conversion of Broad-Spectrum Antimicrobial Peptides into Species-Specific Antimicrobials Capable of Precisely Targeting Pathogenic Bacteria. | Sci Rep | 2020