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Peptide record

TPDB12875

Antibacterial Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12875
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
INWLRLGRRILGAL
Physicochemical Analysis
C76H131N25O16
DCEQHKMFPSTYV
L
1651.03
12.70
3
0
8
+3
-2.01
0.521
174.29
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
333.12
1
Residue Composition
number
1
A
3
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C76H131N25O16
1651.03
12.70
+3
-2.01
0.521
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
50% Hemolysis | 25 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs | Peptides | 2008
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis