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Peptide record

TPDB12872

Antibacterial Cell-penetrating Peptides Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12872
Antibacterial Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0 PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CPPsite3.0, and other sources, with an available 3D structural model.
Sequence
LKKLLKLLKKLLKL
Physicochemical Analysis
C84H162N20O15
ARNDCEQGHIMFPSTWYV
L
1692.34
11.21
6
0
8
+6
1.46
0.500
222.86
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C84H162N20O15
1692.34
11.21
+6
1.46
0.500
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
10% Hemolysis | 5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Proline Hinged Amphipathic α-Helical Peptide Sensitizes Gram-Negative Bacteria to Various Gram-Positive Antibiotics. | J Med Chem | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis