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Peptide record

TPDB12845

Antibacterial Anticancer Antifungal standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12845
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KKIWQRIKNFFQKL
Physicochemical Analysis
C91H145N25O18
ADCEGHMPSTYV
K
1877.31
11.80
5
0
6
+5
1.06
-0.936
83.57
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
292.97
3
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
2
Q
0
G
0
H
2
I
1
L
4
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 2 L: 1 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C91H145N25O18
1877.31
11.80
+5
1.06
-0.936
Evidence Records 10 records
Evidence 1 Activity

Activity

IC50
Antibacterial
25.6 µM

Target

Candida albicans SC5314

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans SC5314 (IC50 25.6 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202
Evidence 2 Activity

Activity

IC50
Antibacterial
4.3 µM

Target

F. oxysporum Fo5176

Source & Reference

dbAMP

Other

Active against C. albicans SC5314 (IC50 25.6 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S.
Evidence 3 Activity

Activity

IC50
Antibacterial
18.8 µM

Target

A. fumigatus CBS117202

Source & Reference

dbAMP

Other

s SC5314 (IC50 25.6 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S. epidermidis (MIC 50 uM), S. enterica s
Evidence 4 Activity

Activity

MIC
Antibacterial
6.25-7.0 µM

Target

Escherichia coli K12 MG1655 or UTI89

Source & Reference

dbAMP

Other

(IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S. epidermidis (MIC 50 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 29 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

M), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S. epidermidis (MIC 50 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 29 uM).
Evidence 6 Activity

Activity

IC50
Antifungal
25.6 µM

Target

Candida albicans SC5314

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against C. albicans SC5314 (IC50 25.6 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202
Evidence 7 Activity

Activity

IC50
Antifungal
4.3 µM

Target

F. oxysporum Fo5176

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against C. albicans SC5314 (IC50 25.6 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S.
Evidence 8 Activity

Activity

IC50
Antifungal
18.8 µM

Target

A. fumigatus CBS117202

Source & Reference

dbAMP CAFPdb Antifungipept

Other

s SC5314 (IC50 25.6 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S. epidermidis (MIC 50 uM), S. enterica s
Evidence 9 Activity

Activity

MIC
Antifungal
6.25-7.0 µM

Target

Escherichia coli K12 MG1655 or UTI89

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(IC50 >50 uM), F. oxysporum Fo5176 (IC50 4.3 uM), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S. epidermidis (MIC 50 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 29 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
50 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

M), A. fumigatus CBS117202 (IC50 18.8 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25-7.0 uM), S. epidermidis (MIC 50 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 29 uM).