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Peptide record

TPDB12815

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12815
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
INWKGIAAMAKKLA
Physicochemical Analysis
C70H119N19O16S1
RDCEQHFPSTYV
A
1514.89
10.84
3
0
9
+3
-0.54
0.386
112.14
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
363.06
1
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
3
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C70H119N19O16S1
1514.89
10.84
+3
-0.54
0.386
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
220±20 µM
Hemolytic Cytotoxic
5% Hemolysis | 220±20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Side chain hydrophobicity modulates therapeutic activity and membrane selectivity of antimicrobial peptide mastoparan-X. | PLoS One | 2014