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Peptide record

TPDB12809

Antibacterial Anticancer Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12809
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GKKYRRFRWKFKGK
Physicochemical Analysis
C90H141N29O16
ANDCEQHILMPSTV
K
1885.29
12.17
8
0
4
+8
2.35
-2.171
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6990
370.76
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
5
K
0
M
2
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
14
C90H141N29O16
1885.29
12.17
+8
2.35
-2.171
Evidence Records 4 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF). | Antibiotics (Basel) | 2020
Evidence 2 Activity

Activity

<10% Hemolysis
Toxicity
300 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 300 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF). | Antibiotics (Basel) | 2020
Evidence 3 Activity

Activity

<10% Hemolysis
Toxicity
37.5 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 37.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF). | Antibiotics (Basel) | 2020
Evidence 4 Activity

Activity

18% Hemolysis
Toxicity
75 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 75 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF). | Antibiotics (Basel) | 2020