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Peptide record

TPDB12779

Antibacterial Anticancer Antifungal standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12779
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KKIWQKIKNFFQKL
Physicochemical Analysis
C91H145N23O18
ARDCEGHMPSTYV
K
1849.30
11.12
5
0
6
+5
1.24
-0.893
83.57
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
297.41
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
2
Q
0
G
0
H
2
I
1
L
5
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 2 L: 1 K: 5 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C91H145N23O18
1849.30
11.12
+5
1.24
-0.893
Evidence Records 10 records
Evidence 1 Activity

Activity

IC50
Antibacterial
23.9 µM

Target

Candida albicans SC5314

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans SC5314 (IC50 23.9 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202
Evidence 2 Activity

Activity

IC50
Antibacterial
3.7 µM

Target

F. oxysporum Fo5176

Source & Reference

dbAMP

Other

Active against C. albicans SC5314 (IC50 23.9 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epi
Evidence 3 Activity

Activity

IC50
Antibacterial
19.4 µM

Target

A. fumigatus CBS117202

Source & Reference

dbAMP

Other

s SC5314 (IC50 23.9 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epidermidis (MIC 29 uM), S. enterica serov
Evidence 4 Activity

Activity

MIC
Antibacterial
6.25 µM

Target

Escherichia coli K12 MG1655 or UTI89

Source & Reference

dbAMP

Other

(IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epidermidis (MIC 29 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 50 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
29 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epidermidis (MIC 29 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 50 uM).
Evidence 6 Activity

Activity

IC50
Antifungal
23.9 µM

Target

Candida albicans SC5314

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against C. albicans SC5314 (IC50 23.9 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202
Evidence 7 Activity

Activity

IC50
Antifungal
3.7 µM

Target

F. oxysporum Fo5176

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against C. albicans SC5314 (IC50 23.9 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epi
Evidence 8 Activity

Activity

IC50
Antifungal
19.4 µM

Target

A. fumigatus CBS117202

Source & Reference

dbAMP CAFPdb Antifungipept

Other

s SC5314 (IC50 23.9 uM), C-glabrata BG2 (IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epidermidis (MIC 29 uM), S. enterica serov
Evidence 9 Activity

Activity

MIC
Antifungal
6.25 µM

Target

Escherichia coli K12 MG1655 or UTI89

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(IC50 >50 uM), F. oxysporum Fo5176 (IC50 3.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epidermidis (MIC 29 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 50 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
29 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

.7 uM), A. fumigatus CBS117202 (IC50 19.4 uM), E. coli K12 MG1655 or UTI89 (MIC 6.25 uM), S. epidermidis (MIC 29 uM), S. enterica serovar Typhimurium ATCC/SL 14028 (MIC 50 uM).