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Peptide record

TPDB12757

Antibacterial Hemolysis Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB12757
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KIAKRIWKILRRRL
Physicochemical Analysis
C86H156N30O15
NDCEQGHMFPSTYV
R
1850.38
12.88
7
0
7
+7
2.14
-0.550
146.43
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
297.24
0
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C86H156N30O15
1850.38
12.88
+7
2.14
-0.550
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
15.63 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 15.63 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel, rationally designed, hybrid antimicrobial peptide, inspired by cathelicidin and aurein, exhibits membrane-active mechanisms against Pseudomonas aeruginosa. | Sci Rep | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel, rationally designed, hybrid antimicrobial peptide, inspired by cathelicidin and aurein, exhibits membrane-active mechanisms against Pseudomonas aeruginosa. | Sci Rep | 2020
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis