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Peptide record

TPDB12750

Antibacterial Anticancer Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12750
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
IPLLRKGKKIIWW
Physicochemical Analysis
C83H135N21O14
ANDCEQHMFSTYV
IK
1651.12
11.73
4
0
7
+4
-1.51
0.085
150.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
11000
666.22
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
3
K
0
M
0
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
13
C83H135N21O14
1651.12
11.73
+4
-1.51
0.085
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
<10% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of antimicrobial and cytolytic peptides by computational analysis of bacterial, algal, and invertebrate proteomes. | Amino Acids | 2020
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: <10% Hemolysis=50 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Amino Acids. 2020 Oct 52(10):1403-1412